Searchable abstracts of presentations at key conferences in endocrinology

ea0059p058 | Clinical biochemistry | SFEBES2018

A cross-sectional study of sensitivity and specificity of late-night salivary cortisol in a single-centre heterogenous population

Barker Sally , Prabhudev Hemanth , Martin Nimah , Todd Jeannie , Meeran Karim , Agha-Jaffar Rochan , Wernig Florian

Endogenous Cushing’s syndrome poses considerable diagnostic challenges. It is recommended to use two screening tests to confirm hypercortisolaemia. While late-night salivary cortisol assessment (LNSC) is reported to have good specificity and sensitivity and deemed to be cost-effective, it is the least widely biochemical tool used both nationally and in Europe. We aim to compare the specificity and sensitivity of LNSC against and in combination with other diagnostic tests,...